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CRISPR Gene Editing News
June 16, 2019

Top Headlines
 

Using Gene Editing, Neuroscientists Develop a New Model for Autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental ... read more

Researchers Use Gene Editing With CRISPR to Treat Lethal Lung Diseases Before Birth

Using CRISPR gene editing, researchers have thwarted a lethal lung disease in an animal model in which a harmful mutation causes death within hours ... read more

A Biosynthetic Dual-Core Cell Computer

Researchers have integrated two CRISPR-Cas9-based core processors into human cells. This represents a huge step towards creating powerful ... read more

CRISPR-Based 'Allelic Drive' Allows Genetic Editing With Selective Precision and Broad Implications

Scientists developed a new version of a gene drive that allows the spread of specific, favorable genetic variants, also known as 'alleles,' ... read more
Latest Headlines
updated 10:22pm EDT

Earlier Headlines
 

Sweet! How C. Difficile Toxin A Enters Intestinal Cells

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness, with the bacterium's toxins causing the damage. New work cements our knowledge of how ... read more

New Genomics Tool ECCITE-Seq Expands Multimodal Single Cell Analysis

ECCITE-seq (Expanded CRISPR-compatible Cellular Indexing of Transcriptomes and Epitopes by sequencing) allows researchers to perform high-throughput measurements of multiple modalities of information ... read more

New DNA 'Shredder' Technique Goes Beyond CRISPR's Scissors

An international team has unveiled a new CRISPR-based tool that acts more like a shredder than the usual scissor-like action of CRISPR-Cas9. The new approach, based on Type I CRISPR-Cas3, is able to ... read more

CRISPR-Chip Enables Digital Detection of DNA Without Amplification

Researchers have found multiple applications for the CRISPR gene editing technology since it came into use by the scientific ... read more

Two-Step Path to Shrinking Worker Bee Gonads

The dramatic difference in gonad size between honey bee queens and their female workers in response to their distinct diets requires the switching on of a specific genetic program, according to a new ... read more

Using More-Specific 'Genetic Scissors' May Avoid Problems Associated With Gene Editing

A new study suggests that there could be a way to bypass barriers to making CRISPR gene-editing treatments a viable option. Researchers found that using more-precise gene-editing technology that ... read more

New Understanding of Sophistication of Microbial Warfare

Researchers explain how viruses make a molecular decoy that is used to subvert the CRISPR-Cas bacterial immune ... read more

Illuminating the Genome

Researchers have developed a new molecular visualisation method, RNA-guided endonuclease -- in situ labelling (RGEN-ISL) for the CRISPR/Cas9-mediated labelling of genomic sequences in nuclei and ... read more

Checking DNA Base Editor's Mistakes and Tricks to Reduce Them

Scientists have identified the mistake-rate of DNA editing tools, based on CRISPR and known as adenine base editors. Assessing the genome-wide target specificity of these innovative techniques is ... read more

Manipulating Gene Expression in Neurons With CRISPR

Neuroscientists have used CRISPR/Cas9 genome editing technology to regulate genes in the rat brain. This technique paves the way for researchers to probe genetic influences on brain health and ... read more

Scientists Sharpen Their Molecular Scissors and Expand the Gene Editing Toolbox

Scientists have figured out a better way to deliver a DNA editing tool to shorten the presence of the editor proteins in the cells in what they describe as a 'hit and run' ... read more

The Novel Method Nested CRISPR Enables Efficient Genome Editing Using Long DNA Fragments

Researchers used the model organism Caenorhabditis elegans to optimize a new technique, leading to the development of the method called Nested CRISPR. This cloning-free method involves the insertion ... read more

New Anti-CRISPR Proteins Discovered in Soil and Human Gut

Scientists have found four new anti-CRISPR proteins that are distributed across different environments. The new study suggests that some anti-CRISPR proteins are more widespread in nature than ... read more

Whopping Big Viruses Prey on Human Gut Bacteria

Sequencing gut microbiomes typically turns up new microbes and other denizens of the intestinal tract, including viruses or phages that prey on these microbes. A new study has discovered the largest ... read more

CRISPR/Cas9 Used to Control Genetic Inheritance in Mice

Using active genetics technology, biologists have developed the world's first CRISPR/Cas9-based approach to control genetic inheritance in a mammal. The achievement in mice lays the groundwork ... read more

Effective Strategies for Safeguarding CRISPR Gene-Drive Experiments

Researchers have demonstrated for the first time how two molecular strategies can safeguard CRISPR gene-drive experiments in the lab, according to a new ... read more

Potential Biotech and Health Applications With New Knowledge on Bacteria and Viruses

New research to better understand how bacteria and their viruses interact and evolve will enable future studies to exploit the use of bacteria and their viruses for potential biotechnology and health ... read more

Gene-Editing Tool CRISPR/Cas9 Shown to Limit Impact of Certain Parasitic Diseases

Researchers have successfully used CRISPR/Cas9 to limit the impact of schistosomiasis and liver fluke infection, which affects more than a quarter of a billion people in Southeast Asia, sub-Saharan ... read more

Gene-Editing Tool CRISPR Repurposed to Develop Better Antibiotics

Scientists have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ... read more

Targeting an RNA-Binding Protein to Fight Aging

Researchers have found that the RNA-binding protein PUM2 contributes to the accumulation of defective mitochondria, a key feature of the aging process. Targeting PUM2 in old animals protects against ... read more

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