Huntington's Disease News
June 26, 2019

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Abnormalities in a Protein Affecting How Nerve Cells Change Shape

Since 1993, when the gene that causes Huntington's disease (HD) was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe ... read more

A New Hope in Treating Neurodegenerative Disease

Researchers have clarified the fundamentals of coiled toxin protein which causes neurodegenerative brain disorders. The result is expected to speed the development of treatment for neurodegenerative ... read more

The Brain's Support Cells Show Defective Development in Huntington's Disease

The neurological disorder Huntington's disease causes behavioral and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the ... read more

Predict the Onset and Course of Huntington's Disease

Short protein fibers precede the formation of larger deposits that accumulate in the brains of those affected by the incurable Huntington's disease, sometimes called Huntington's chorea, ... read more

Earlier Diagnosis, Potential Therapy for Huntington's Disease Suggested in New Research

A new study suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the ... read more

Powerful Molecules Provide New Findings About Huntington's Disease

Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's ... read more

Researchers Discover System That Could Reduce Neurodegeneration in Huntington's Disease

Neuroscientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease. Particularly, they identified a system blocking ... read more

Powerful New Approach Helps Understand Molecular Alterations in Neurological Disease

Scientists have developed a high-throughput, multi-pronged approach that integrates laboratory experiments, data from published literature and network analysis of large datasets to identify genes ... read more

New Piece in the Huntington's Disease Puzzle

Researchers have discovered a previously unknown error in the transport of glutamine between astrocytes and neurons in the brain of mice with Huntington's disease. At the same time, it is a ... read more

Pig Model of Huntington's Offers Advantages for Testing Treatments

A team of scientists has established a 'knock in' pig model of Huntington's disease (HD), an inherited neurodegenerative disease, anticipated to be useful for testing ... read more

Medical Tests With Less Fear

It is a principle of modern architecture that less may be more. This principle does not apply to information as a basis of far-reaching decisions, it seems. But: Many people shy away from going to ... read more

Strict Eating Schedule Can Lower Huntington Disease Protein in Mice

New research suggests that following a strict eating schedule can help clear away the protein responsible for Huntington disease in ... read more

Decoding the Structure of Huntingtin

Determining the three dimensional structure of the huntingtin protein could help develop new treatments for Huntington's ... read more

Huntington's Disease Provides New Cancer Weapon

Patients with Huntington's disease, a fatal genetic illness that causes the breakdown of nerve cells in the brain, have up to 80 percent less cancer than the general population. Scientists have ... read more

Altering Huntington's Patients' Skin Cells Into Brain Cells Sheds Light on Disease

Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder. The resulting mass of neurons serves as a new tool to study ... read more

Uncovering the Early Origins of Huntington's Disease

The symptoms of Huntington's disease typically appear in middle age, but new research shows that neural abnormalities are evident much earlier, in the first steps of embryonic development. The ... read more

Commonalities in Brains of People With Huntington's Disease and Parkinson's Disease

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, ... read more

Scheduled Feeding Improves Neurodegenerative Symptoms in Mice

Restricting meals to the same time each day improves motor activity and sleep quality in a mouse model of Huntington's disease, according to new research. These findings suggest that eating on a ... read more

Possible Biomarker for Huntington's Disease

A new discovery of a potential biomarker for Huntington's disease (HD) could mean a more effective way of evaluating the effectiveness of treatments for this neurological disease. The findings ... read more

Drug Lowers Deadly Huntington's Disease Protein

The first drug targeting the cause of Huntington's disease was safe and well-tolerated in its first human trial, and successfully lowered the level of the harmful huntingtin protein in the ... read more

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