Cocaine News
June 16, 2019

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updated 10:18pm EDT

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Cell-Type Specific Mechanism for Formation and Retrieval of Cocaine-Associated Memories

Scientists have revealed neuronal mechanisms underlying the formation and retrieval of cocaine use-associated memories. Their research sheds light on how drug addiction develops and reveals pathways ... read more

Performance-Enhancing Drugs May Increase Risk of Teen Cocaine Abuse, Impair Fertility

Performance-enhancing steroid use could increase the risk of cocaine use and addiction in teens, according to a new rodent study. The combination of these drugs could also impair fertility in young ... read more

Menstrual Cycle Phase Influences Cocaine Craving

Menstrual cycle may influence addiction risk in women, according to a new ... read more

How Exercise Could Help Fight Drug Addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder. However, addicts who exercise appear ... read more

Cluster of Cocaine-Fentanyl Overdoses in Philadelphia Underscores Need for More 'Test Strips' and Rapid Response

Emergency department physicians are calling for more readily available testing strips to identify the presence of fentanyl in patients experiencing a drug overdose, and a rapid, coordinated response ... read more

Drug Overdose Epidemic Has Been Growing Exponentially for Decades

Death rates from drug overdoses in the US have been on an exponential growth curve that began at least 15 years before the mid-1990s surge in opioid prescribing, suggesting that overdose death rates ... read more

Gene Therapy Via Skin Protects Mice from Lethal Cocaine Doses

A new study shows that skin stem cells, modified via CRISPR and transplanted back to donor mice, can protect addicted mice from cocaine-seeking and ... read more

Cocaine Addiction Traced to Increase in Number of Orexin Neurons

A new study identifies a critical role of the orexin system in the expression of an addicted state in ... read more

Investigators Find That Bile Acids Reduce Cocaine Reward

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new ... read more

Racial Disparities in Prescribing Opioids for Chronic Pain

Researchers have identified racial disparities in the treatment of patients who are prescribed opioids for chronic pain. Black patients who receive opioids long-term are more likely than whites to be ... read more

SMURF1 Provides Targeted Approach to Preventing Cocaine Addiction Relapse

A class of proteins that has generated significant interest for its potential to treat diseases, has for the first time, been shown to be effective in reducing relapse, or drug-seeking behaviors, in ... read more

Exercise Can Help Beat Cocaine Addiction, Study Finds

Exercise can help prevent relapses into cocaine addiction, according to new ... read more

Cocaine Relapse Is Reversed With BDNF Microinjections in the Brain

Investigators discover that brain-derived neurotropic factor reduced cocaine relapse in a preclinical model when administered before a cue-induced relapse ... read more

Bile Acids from the Gut Could Help to Treat Cocaine Abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a new ... read more

Childhood Adversity Increases Susceptibility to Addiction Via Immune Response

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a new ... read more

Hunger Hormones Offer Promising Avenue for Addiction Treatment

Hormones that signal the body's state of hunger and fullness could be the key to new treatments for drug and alcohol addiction. Gut hormones have received considerable attention from scientists ... read more

A Gene Required for Addictive Behavior

Cocaine can have a devastating effect on people. It directly stimulates the brain's reward center, and, more importantly, induces long-term changes to the reward circuitry that are responsible ... read more

Newly Developed Therapeutic Shown to Combat Drug Addiction

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug ... read more

Potential New Treatment for Drug Addiction Relapse Revealed

Research reveals a new potential mechanism for combating drug addiction ... read more

Cocaine Use Alters Gene Expression in Brain Reward Circuits

A study has identified unique genetic changes in the brain's reward circuitry that are associated with cocaine use, including first-time use, withdrawal, and re-exposure to the drug after ... read more

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