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Pharmacology News
May 19, 2019

Top Headlines
 

Electric Field-Based Dressing Helps Heal Wound Infections

Researchers have found a way to charge up the fight against bacterial infections using electricity. Scientists have developed a dressing that uses an electric field to disrupt biofilm infection in ... read more

Toy Transformers and Real-Life Whales Inspire Biohybrid Robot

Researchers create a remote-controlled soft robot that can transform itself to conduct targeted drug delivery against cancer ... read more

Early Weight-Loss Surgery May Improve Type 2 Diabetes, Blood Pressure Outcomes

Despite similar weight loss, teens who had gastric bypass surgery were significantly more likely to have remission of both type 2 diabetes and high ... read more
A cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order ... read more
Latest Headlines
updated 4:47am EDT

Earlier Headlines
 

Clinical Trial Improves Treatment of Genetic Rickets

A new study shows a drug to alleviate symptoms of a rare musculoskeletal condition is significantly more effective than conventional ... read more

A New Approach to Targeting Cancer Cells

A research team has come up with a new approach to targeting cancer cells that circumvents a challenge faced by currently available cancer ... read more

Why Lymphoma Patients May Become Resistant to Specific Therapy

Researchers have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid ... read more

Ragweed Compounds Could Protect Nerve Cells from Alzheimer's

As spring arrives in the northern hemisphere, many people are cursing ragweed, a primary culprit in seasonal allergies. But scientists might have discovered a promising new use for some substances ... read more

Researchers Block Protein That Plays a Key Role in Alzheimer's Disease

In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study now shows the de facto key role played by the ... read more

Enzyme PHLPP2 Could Be a Viable Drug Target for Treating Prostate Cancer

Researchers propose a new druggable target that can put a damper on the spread of prostate cancer. Containing the threat at its origin organ greatly increases the survival rates of patients who ... read more

Molecular Basis of Brain Dysfunction and Embryo Malformation Associated With Thalidomide

Scientists have identified the molecule involved in thalidomide-related dysfunctions associated with in utero brain and organ development. Their in vivo results using a zebrafish model of mammalian ... read more

Researchers identify exact cells mediating the mouse's defense against Staphylococcus infection ... read more

Big Data Helps Identify Better Way to Research Breast Cancer's Spread

Researchers are analyzing large volumes of data, often referred to as big data, to determine better research models to fight the spread of breast cancer and test potential drugs. Current models used ... read more

Researchers Identify Faster, More Effective Drug Combinations to Treat Tuberculosis

A new study describes a way to reduce the duration of tuberculosis treatment by using an approach called 'artificial intelligence-parabolic response surface' that allows researchers to ... read more

Five Rules to Tackle Antibiotic Resistance

Current efforts to tackle antibiotic resistance are 'not nearly radical enough,' a leading scientist ... read more

Plaque in Arteries May Not All Be the Same; Targeting Specific Immune Cells in Plaque May Reduce Heart Attack and Stroke Risk

A specific type of immune cell is more commonly found in arterial plaque from patients suffering from a recent stroke or mini-stroke, according to preliminary ... read more

Early in Vitro Testing for Adverse Effects on Embryos

Researchers have combined embryonic cells and liver cells in a new cell culture test. This combination lets them detect adverse effects that new medications may have on embryos early on in the drug ... read more

Brain Changes Linked With Alzheimer's Years Before Symptoms Appear

In a records review of 290 people at risk for Alzheimer's disease, scientists say they have identified an average level of biological and anatomical brain changes linked to Alzheimer's ... read more

Historically 'Safer' Tramadol More Likely Than Other Opioids to Result in Prolonged Use

Surgical patients receiving the opioid tramadol have a somewhat higher risk of prolonged use than those receiving other common opioids, new research finds. However, the Drug Enforcement ... read more

Regular coffee drinkers can sniff out even tiny amounts of coffee and are faster at recognizing the aroma, which could open the door to new ways of using aversion therapy for ... read more

Conquering Cancer's Infamous KRAS Mutation

Scientists have shown that a compound called PHT-7.3 shrinks KRAS-driven tumors in mice. In contrast to directly targeting mutant KRAS, the potential drug candidate targets the protein's partner ... read more

A research team has developed an approach to co-culture a complex human gut microbiome in direct contact with intestinal tissue for at least five days using 'organ-on-a-chip' (Organ Chip) ... read more

Research uncovers key mechanism that allows some of the deadliest human RNA viruses to orchestrate the precise copying of the individual pieces of their viral genome and replicate. The findings ... read more

Treatment Targets for Men With Advanced Prostate Cancers

A study outlines findings from the largest-ever prospective genomic analysis of advanced prostate cancer tumors. Using comprehensive genomic profiling (CGP) to analyze thousands of tumor samples from ... read more

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