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Multiple Myeloma News
June 17, 2019

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Cardiac Toxicity Risk Factors Identified With Relapsed Multiple Myeloma Therapy

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study. The study recommends that ... read more

Blood Cancer Precursor Found in 9/11 Firefighters

A new study reports that New York City firefighters exposed to the 9/11 World Trade Center disaster site face an increased risk for developing myeloma precursor disease (MGUS), which can lead to the ... read more

Chip-Based Blood Test for Multiple Myeloma Could Make Bone Biopsies a Relic of the Past

A new research effort has resulted in a low-cost, reliable blood test that uses a small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone biopsy ... read more

Changes in Genes Involved in DNA Repair and Packaging Linked to Risk of Multiple Myeloma

Researchers have identified two gene regions that contribute to multiple myeloma, an inherited cancer that occurs in bone marrow, through a new method that makes use of human disease ... read more

Light-Triggered Nanoparticles Show Promise Against Metastatic Cancer

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy -- which is limited to the skin and areas accessible with an endoscope -- this technique can target and ... read more

Patients With Blood Cancer Precursor at Risk of Developing Cancer Even After 30 Years

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer even after 30 years of ... read more

Carfilzomib Can Lead to Cardiovascular Toxicity in Multiple Myeloma Patients

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research shows the therapy comes with the risk of cardiovascular problems in a ... read more

CT Scans of Egyptian Mummies Reveal Oldest Known Cases of Breast Cancer and Multiple Myeloma

An international team has discovered the world's oldest known cases of breast cancer and multiple myeloma (a type of bone marrow cancer). The discoveries were made by conducting CT scans of two ... read more

In Multiple Myeloma, High Levels of Enzyme ADAR1 Are Associated With Reduced Survival

Using a database of multiple myeloma patient samples and information, researchers found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme ... read more

One-Size Treatment for Blood Cancer Probably Doesn't Fit All, Researchers Say

Though African-American men are three times more likely to be diagnosed with a blood cancer called multiple myeloma, most scientific research on the disease has been based on people of European ... read more

Cell-Weighing Method Could Help Doctors Choose Cancer Drugs

Researchers can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple myeloma patients. Their predictions correlated with how those patients actually fared ... read more

Test Results After Stem Cell Transplant for Multiple Myeloma Can Confuse Patients and Doctors About Cancer's Status

It's a cancer of the plasma cells, which normally make an array of antibodies that protect us from infection. With multiple myeloma, the cells start primarily producing instead a singular ... read more

Promising New Therapeutic Approach for Debilitating Bone Disease

A new type of therapeutic could greatly reduce bone disease in patients with the bone cancer, multiple myeloma. Multiple myeloma is a cancer that develops in bone, causing progressive bone ... read more

CAR T-Cell Therapy Sends Multiple Myeloma Into Lasting Remission

In an early clinical trial, 33 out of 35 (94 percent) patients had clinical remission of multiple myeloma upon receiving a new type of immunotherapy -- chimeric antigen receptor (CAR) T cells ... read more

Therapy Shrinks Tumors in Patients With Multiple Myeloma

An experimental drug, LCL161, stimulates the immune system, leading to tumor shrinkage in patients affected by multiple myeloma, report ... read more

Using a Rabbit Virus to Treat Multiple Myeloma

Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators. Furthermore, introduction of MYXV had no impact on the ... read more

Engineering Team Finds Compound May Halt Molecular Cause of Often-Fatal Condition

A team of engineers say a compound found in green tea could have lifesaving potential for patients with multiple myeloma and amyloidosis, who face often-fatal medical complications associated with ... read more

Inhibition of EZH2 Might Be New Multiple Myeloma Therapy

In a new study, researchers in Sweden show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease. The ... read more

Aggressive Form of Leukemia Linked to Defective 'Protein Factory'

20 to 40 percent of the patients with multiple myeloma -- a type of leukemia -- have a defect in the ribosome, the protein factory of the cell. These patients have a poorer prognosis than patients ... read more

Weight Loss May Help Prevent Multiple Myeloma

Carrying extra weight increases a person's risk that a benign blood disorder will develop into multiple myeloma, a blood cancer. This is particularly true for older, African-American men, say ... read more

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