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Human Biology News
May 22, 2019

Top Headlines
 

Why Lack of Sleep Is Bad for Your Heart

People who sleep fewer than 7 hours per night have lower levels of gene-regulating molecules, or microRNAs, which help dampen down inflammation in cells and support vascular ... read more

Protein That Hinders Advancement of Prostate Cancer Identified

Researchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer ... read more

Stroke, Cancer and Heart Disease: Key Acid-Activated Protein Channel

Researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of ... read more
Up to one in seven kidney donors and recipients may have a type of genetic incompatibility that leads to organ rejection, researchers ... read more
Latest Headlines
updated 4:47am EDT

Earlier Headlines
 

Mining 25 Years of Data Uncovers a New Predictor of Age of Onset for Huntington Disease

Investigators have examined more than 25 years of data to reveal new insights into predicting the age of onset for Huntington ... read more

Why Lymphoma Patients May Become Resistant to Specific Therapy

Researchers have discovered a mechanism of drug resistance to Venetoclax®, also known as ABT-199, a BCL-2 targeting drug commonly used to treat chronic lymphocytic leukemia and acute myeloid ... read more

New Doctors' DNA Ages Six Times Faster Than Normal in First Year

Every summer, tens of thousands of newly minted doctors start the most intense year of their training: the first year of residency, also called the intern year. A new study suggests that the ... read more

Plaque in Arteries May Not All Be the Same; Targeting Specific Immune Cells in Plaque May Reduce Heart Attack and Stroke Risk

A specific type of immune cell is more commonly found in arterial plaque from patients suffering from a recent stroke or mini-stroke, according to preliminary ... read more

A research team has developed an approach to co-culture a complex human gut microbiome in direct contact with intestinal tissue for at least five days using 'organ-on-a-chip' (Organ Chip) ... read more

Research uncovers key mechanism that allows some of the deadliest human RNA viruses to orchestrate the precise copying of the individual pieces of their viral genome and replicate. The findings ... read more

How Mutations Lead to Neurodegenerative Disease

Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of ... read more

Prince Charming's Kiss Unlocking Brain's Regenerative Potential?

Researchers find that 'waves' of Hes1 and Ascl1 gene expression control the quiescent and active state of adult neural stem cells. Hes1 expression promotes quiescence and suppresses Ascl1, ... read more

Multiple Sclerosis: Discovery of a Mechanism Responsible for Chronic Inflammation

Multiple sclerosis (MS) is an autoimmune disease. The defense system that usually protects patients from external aggression turns on its own cells and attacks them for reasons that are not yet ... read more

Scientists have studied potential cancer suppression mechanisms in cetaceans, the mammalian group that includes whales, dolphins and porpoises. Biologists picked apart the genome of the humpback ... read more

A Deep-Dive Into the Impact of Arthritis Drugs on Gene Expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in ... read more

How the Dengue Virus Replicates in Infected Cells

The nonstructural protein 1 (NS1) of the dengue virus interacts with another viral protein called NS4A-2K-4B to enable viral replication, according to a new ... read more

Egg Yolk Precursor Protein Regulates Mosquitoes' Attraction to Humans

Feeding mosquitoes sugar makes them less attracted to humans, a response that is regulated by the protein vitellogenin, according to a new ... read more

Personalized 'Eye-in-a-Dish' Models Reveal Genetic Underpinnings of Macular Degeneration

Using stem cells derived from six people, researchers recapitulated retinal cells in the lab. This 'eye-in-a-dish' model allowed them to identify genetic variants that cause age-related ... read more

A Cautionary Tale for Researchers Working on Selective Drug Delivery

Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are flawed, according to new ... read more

Painting a Fuller Picture of How Antibiotics Kill

Researchers have used machine-learning algorithms to discover a secondary mechanism that helps some antibiotics kill bacteria. This mechanism involves disrupting bacterial metabolism of nucleotides ... read more

Innovative Mechanobiology Research Expands Understanding of Cells

Researchers have developed a new technology that allows them to probe cell changes without disturbing the cell's physiology -- a major advancement that helps scientists look more closely at cell ... read more

Researchers have found that therapy that can induce heart cells to regenerate after a heart ... read more

Advancing Cell Therapy for Diabetes

Researchers used single-cell sequencing to identify a protein expressed uniquely by insulin-producing beta cells created from stem cells in the laboratory. By targeting the protein and adding a ... read more

Creating a Global Map of the Protein Shape Universe

Researchers have come up with a novel way to classify proteins and their shapes, which lays the foundation of how we understand protein structures and ... read more

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